Speakers

DÉBORA SOUZA

UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL

BRAZIL

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Talk:

Aging reshapes brain metabolic network and protein profile.

Dr. Souza has been working with in vitro models of glial cells aiming at unveiling astroglial role in neuroenergetics and brain homeostasis in physiology and pathology. Dr. Souza's main research interest is the understanding of the astrocyte/neuron relationship during aging, its implications for neurodegenerative diseases and possible strategies to improve it.

JULIA CLARKE

UNIVERSIDADE FEDERAL DO RIO DE JANEIRO

BRAZIL

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Talks:

- Late neurological consequences of early-life infections.

- Opportunities at UFRJ.

Dr. Clarke research has been focused on understanding brain metabolism and reprogramming in the course of neurological conditions, such as Alzheimer´s and Parkinson´s diseases. In the past few years she has also been investigating the acute and chronic neurological consequences of Zika virus infection.

MARCELO MORI

UNICAMP

BRAZIL

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Talks:

- C. elegans as an elegant tool to study neuronal function, metabolism and aging.

- Opportunities at Unicamp.

Dr. Mori is an affiliated member of the Brazilian Scientific Academy and is interested in the identification and characterization of molecular mechanisms involved in the pathophysiology of aging. Dr. Mori has experience in molecular biology with focus in metabolism, specially investigating the molecular mechanisms associated to metabolic syndrome, diabetes, cardiovascular diseases and neurodegenerative disorders.

MICHAEL SCHÖLL

UNIVERSITY OF GOTHENBURG

SWEDEN

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Talks:

- Update on what we believe is tau imaging.

- Opportunities at University of Gothenburg.

Dr. Schöll research aims to identify, using neuroimaging, neuropathological changes at the earliest possible stage. It allows differentiate a brain that will eventually develop a neurodegenerative disease, such as a dementia disorder, from a brain that will age healthily. Currently he is working with TAU imaging.

NICHOLAS ASHTON

UNIVERSITY OF GOTHENBURG

SWEDEN

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Talks:

- A fluid-based test for Alzheimer's disease and related disorders; from CSF to blood.

- Measuring brain derived proteins in fluid; the technology and the advances.

Dr. Ashton research focuses on using fluid-based biomarkers to complement quantitative imaging assessments for the early detection of dementia risk. Dr. Ashton has a technical background in Mass Spectrometry and immunological-based assays which has been utilized more recently to develop blood signatures of Alzheimer’s disease neuropathology.

RAFAEL ROESLER

UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL

BRAZIL

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Talk:

- Opening Lecture.

Dr. Roesler is the Pro-Rector of Research at the Universidade Federal do Rio Grande do Sul. In 2007, he was elected an Affiliate Member of the Brazilian Academy of Sciences and he is currently the coordinator of the Laboratory of Cancer and Neurobiology at the Hospital de Clínicas of Porto Alegre. Dr. Roesler mainly interest is the pharmacology of neural tumors, the investigation of neuropeptide/neurotrophin signaling and the epigenetic mechanisms in cancer.

THARICK PASCOAL

MCGILL UNIVERSITY

CANADA

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Talks:

- The associations between pathological pathways in the progression of Alzheimer’s disease.

- Imaging brain epigenetics in Alzheimer’s disease.

Dr. Pascoal is currently working with the earliest clinical manifestations, metabolic and morphologic abnormalities underlying Alzheimer’s disease pathophysiology in a neuroimaging perspective. Dr. Pascoal is specially interested in the development of models to predict disease progression using the interface between amyloid pathology and neurodegeneration.

11th Thursday: Auditório da Faculdade de Farmácia da UFRGS  - Av. Ipiranga, 2752

12th Friday: Auditório da Faculdade de Enfermagem da UFRGS - Av. São Manoel, 963

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SEMINARS IN BRAIN

DISORDERS III

Fapergs/AOE - 18/2551-0001080-4